Elise Champeil

Elise Champeil

Associate Professor
Phone number: 
646.557.4502
Room number: 
05.66.15NB

Education

 PhD     Trinity College, University of Dublin, Ireland 
MS       Ecole Nationale Superieure de Chimie de Lille, France

Bio

Research interests include:
DNA-mitomycin C adducts formation. Synthesis and NMR characterization.
Detection of drugs of abuse by NMR spectroscopy.
Molecular modeling.
Fullerene chemistry.
Synthesis of molecular sensors.

Publications

Publications

 

Publications (Total number of published journal publications: 16, conference proceedings: 8, invited chapter: 1, invited presentations: 5)

 

Peer Reviewed Articles:

 

1- Champeil E., Paz M., Lukasiewicz E., Kong W., Watson  S., Sapse A.M.“Synthesis of a major mitomycin C DNA adduct via a triaminomitosene”. Bioorganic and Medicinal Chemistry Letters, 22, 2012 7198.

2- Lesar C.T., Decatur J., Luckasiewicz E., Champeil E.“Identification of Gamma-Hydroxybutyric acid (GHB) and Gamma-Butyrolactone (GBL) in beverages using NMR and the PURGE solvent-suppression technique”. Forensic Science International, 212, 2011 40.

3-Sapse D., Champeil E., Sapse A.M. “Theoretical Calculations Applied to the study of the energetics of Reactions of Methamphetamine Synthesis”, Compte rendu des Séances de l’Académie Francaise, 14, 2011 503.

4-Bargonetti J., Champeil E., Tomasz M. “Differential toxicity of DNA adducts of Mitomycin C”, Journal of Nucleic Acids, 2010 Article ID 698960, available on line. DOI:10.4061/2010/698960.

5- Weng M-W, Zheng Y., Jasti V.P., Champeil E., Tomasz M., Wang Y., Basu A.K., Tang M.-S. “Repair of mitomycin C mono- and interstrand cross-linked DNA adducts by UvrABC: a new model”, Nucleic Acid Research, 38, 2010 6976.

6- Liu J., Proni G., Champeil E. “Identification and quantitation of 3,4-methylenedioxy-N-methylamphetamine (MDMA, ecstasy) in human urine by 1H NMR spectroscopy. Application to five cases of intoxication”, Forensic Science International, 194, 2010 103.

7-Champeil E., Proni G., Sapse D. S.“Ab Initio studies of receptor interactions with AMPA ((S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl) propionic acid ) and kainic acid (2S-(2?,3ß,4ß))-2-carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid”  Journal of Molecular Modeling, 15, 2009 1109.

8-Paz M., Ladwa S., Champeil E., Tang L.-Q., Rockwell S., Boamah E., Bargonetti-Chavarria J., Callahan J., Roach J., Tomasz M. “Mapping DNA adducts of mitomycin C and decarbamoyl mitomycin C in cell lines using liquid chromatography/ electrospray tandem mass spectrometry” Chemical Research in Toxicology, 21, 2008 2370.

9-Champeil E., Crean C., Larraya C., Pesticelli G., Proni G., Ghosez L. “Functionalization of C60 via organometallic reagents” Tetrahedron, 64, 2008 10319.

10- Sapse D. S., Champeil E., Maddaluno J., Fressigne C., Sapse A.-M. Ab initio study of the interaction of DNA fragments with methyllithium Compte rendu des Séances de l’Académie Francaise, 11, 2008 1262.

11- Champeil E., Paz M., Ladwa S., Clement C., Zatorski A., Tomasz M. “Synthesis of an Oligodeoxyribonucleotide Adduct of Mitomycin C by the Postoligomerization Method via a Triamino Mitosene” Journal of American Society, 130, 2008 9556.
12- Champeil E., Pradham P., Lakshman M. K. “Palladium-catalyzed Synthesis of Nucleoside adducts from Bay and Fjord Region Diol epoxides” Journal of Organic Chemistry, 72, 2007 5035.

13- Champeil E., Draper S. M. “Ferrocenylalkynes as ligands in transition metal complexes”

Journal of the Chemical  Society, Dalton Transaction, 9, 2001 1440.

14-Braga D., Draper S. M., Champeil E., Grepioni F. “Inorganic-organometallic crystal synthesis. The role of charge-assisted C-H…O and C-H…Cl hydrogen bonds in crystalline [(C5H5)2Co][H2PO4].3H2O and [(C6H5Me)2Cr][Cl] ”Journal of Organometallic Chemistry, 573, 1999 73.

15-Draper S. M., Delamesiere M., Champeil E., Twamley B., Byrne J. J., Long C. “Novel acetylene-linked di-cobalt and tetra-cobalt carbonyl clusters” Journal of Organometallic Chemistry, 589, 1999 157.

16-O’Callaghan C. N., McMurry T. B. H., Draper S. M., Champeil E. “Nitrile and non-nitrile pyridine products from the reaction of 2-cyano-3-(X-nitrophenyl)prop-2-enamides with methyl 3-oxobutanoate” Journal of chemical research-S, 1999 690A.

 

Editorial:

Champeil E. Fighting the War on Drugs: What Weapons for Analysis and Detection?”  Journal of Forensic Toxicology and Pharmacology” 2012, 1:1

 

Scholarly Book Chapter:

“Magnetic resonance spectroscopy: a powerful tool for the identification and quantitation of drugs of abuse in bio-fluids”

Title of the book “Advances in Forensic Science and Application to Law ”. CRC publishers. Editors : Lawrence Kobilinsky, Danielle Sapse. 2012.

 

Expertise

Synthetic Organic Chemistry

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