Ekaterina Korobkova

Ekaterina Korobkova

Ekaterina Korobkova
Assistant Professor
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2004   PhD       -    The University of Chicago (Biophysical Chemistry)
2001   MS         -    Boston University (Physical Chemistry)
1999  Diploma  -    Novosibirsk State University, Russia (Chemistry)


My research focus is DNA damage caused by psychiatric drugs, environmental pollutants, antitumor drugs, poisons, and metals. I am interested in the mechanisms of DNA binding and the structure of the resulting complexes. Covalent modifications on DNA can be used as a marker of a poison or a suicidal drug and utilized in forensic investigations. Once a lesion is formed on DNA a cell sends out a signal for repair. Reactive intermediates of the drugs however can also affect DNA repair proteins. I am interested in studying the dynamics of the complex biochemical cellular response of to the external agents.

Reasearch Interest: DNA damage, DNA repair, psychotropic drugs, dynamics of cellular networks.
My publications include:
1. Ekaterina A. Korobkova, William Ng, Abhishek Venkatratnam, Alicia K. Williams, Madina Nizamova, and Nikolay Azar, Chem. Res. Toxicol,. “In-vitro studies of DNA damage caused by tricyclic antidepressants: a role of peroxidase in side effects of the drugs”, 2010, 23, 1497-1503.

2. Jason Chen, Ekaterina Korobkova, Heng Zhu, and Chuan He, Nat. Methods, “A proteome chip approach reveals new DNA damage recognition activities in Escherichia coli”, 2008, 5 (1), 69-74.

3. Ekaterina A. Korobkova, Thierry Emonet, Heungwon Park, and Philippe Cluzel, Phys. Rev. Lett., “Hidden stochastic nature of a single bacterial motor”, 2006, 96, 058105-1 – 058105-4.

4. Ekaterina Korobkova, Thierry Emonet, Jose M. G. Vilar, Thomas S. Shimizu, Philippe Cluzel, Nature, “From molecular noise to behavioral variability in a single bacterium”, 2004, 428 (6982), 574-578.



Area of Expertise

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Biochemistry, Biophysics, Physical Chemistry

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