Transitioning from IRBManager to Cayuse

Important Dates

06/15/2026 — Deadline to submit Annual Check-Ins and Continuing Reviews for projects expiring before 08/30/2026.

06/22/2026 — Deadline to submit a new IRB application in IRBManager.

06/26/2026 ­­— Deadline to submit Amendments or Final Reports for existing protocols on IRBManager.

07/06/2026 – 08/03/2026 — “Quiet Period”: IRBManager will NOT be available as we complete legacy data migration. 

08/03/2026 — Cayuse go-live target date.

Next Steps 

We will continue to keep the research community informed as the Cayuse implementation schedule and training resources are released. Clear guidance will be shared to support researchers throughout the transition. 

Key Steps to Prepare for the Cayuse Transition

Please check the expiration dates for your existing/open protocol forms on IRBManager. If your due date is before 08/30/2026, you must submit your Annual Check-In or Continuing Review by 06/15/2026.

Please review your studies and submit final reports for projects that are complete. Final reports should be submitted in the following scenarios: 

  • All data collection and interaction with participants have concluded 
  • Data analysis is complete and no further research activities are planned 
  • Data analysis is being conducted only with fully de‑identified data, with no remaining identifiers or links to participants 
  • The project has ended due to lack of funding, feasibility, or other reasons 
  • A student researcher (e.g., thesis or dissertation project) has completed or exited the program 

Important Student and Faculty Considerations: 

  • If a student researcher has graduated or left the program, please ensure that a final report has been submitted for the study. 
  • If human subjects research activities will continue under the faculty advisor or another CUNY Principal Investigator (PI), submit an amendment to remove the former student and to identify the new PI. 

Note: Activities constitute human subjects research when they involve obtaining data through interaction or intervention, or accessing identifiable private information. 

To help avoid delays, please submit any new IRB applications for research intended to begin during the summer as soon as possible.  The deadline for submitting a new IRB application in IRBManager is 06/22/2026.   

The deadline for submitting Amendments and Final Reports is 06/26/2026

IRBManager will be phased out as part of the transition. Please download and securely save all relevant protocol documents for any active studies, and any studies for which you are required to retain records, including: 

  • Approved applications, amendments, and continuing reviews 
  • Approval letters 
  • Approved study materials, such as recruitment materials, consent and assent forms, debriefing materials, surveys, interview guides, scripts, instruments, or other participant‑facing documents 

These materials may be useful for reference once Cayuse goes live. 

See instructions for how to download your attachments.pdf

We will continue to keep the research community informed as the Cayuse implementation schedule and training resources are released. Clear guidance will be shared to support researchers throughout the transition.